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LNP023 hydrochloride
CAS No. 1646321-63-2
LNP023 hydrochloride ( Iptacopan HCl )
Catalog No. M23738 CAS No. 1646321-63-2
LNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 295 | In Stock |
|
| 10MG | 507 | In Stock |
|
| 25MG | 791 | In Stock |
|
| 50MG | 1071 | In Stock |
|
| 100MG | 1458 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLNP023 hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionLNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM.
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DescriptionLNP023 hydrochloride is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM. LNP023 shows direct, reversible, and high-affinity binding to human factor B with a KD of 7.9 nM.
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SynonymsIptacopan HCl
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PathwayOthers
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TargetOther Targets
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Recptorfactor B
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Research Area——
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Indication——
Chemical Information
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CAS Number1646321-63-2
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Formula Weight459.0
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Molecular FormulaC25H31ClN2O4
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Purity>98% (HPLC)
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SolubilityDMSO:250 mg/mL (544.69 mM; Need ultrasonic);H2O:50 mg/mL (108.94 mM; ultrasonic and warming)
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SMILESO=C(O)C1=CC=C([C@H]2N(CC3=C(OC)C=C(C)C4=C3C=CN4)CC[C@H](OCC)C2)C=C1.[H]Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Dimitrios C Mastellos, et al. Expanding Complement Therapeutics for the Treatment of Paroxysmal Nocturnal Hemoglobinuria. Semin Hematol. 2018 Jul;55(3):167-175.
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